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PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) is a
peptide coupling reagent used in
solid phase peptide synthesis. It is used...
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differ only in the
choice of anion.
Phosphonium reagents include PyBOP (HOBt) and
PyAOP (HOAt).[citation needed]
These reagents form the same
active ester...
- the
reduction of
carboxylic acids,
using the
BOP reagent with NaBH4
resulted in high
percent yields.
PyBOP, a
related reagent "(Benzotriazol-1-yloxy)t...
- RC(O)NR'2 + RCO2H
Peptide synthesis use
coupling agents such as HATU, HOBt, or
PyBOP. The
hydrolysis of
nitriles is
conducted on an
industrial scale to produce...
- HOBt derivates,
PyAOP (and HOAt in general) are more
reactive due to the
additional nitrogen. HOAt
reagent HOBt
reagent BOP reagent PyBOP Albericio, F.;...
-
displaces the
benzotriazole N-oxide to form the
desired amide. EDC HATU
BOP reagent PyBOP PyAOP
reagent CID 2733084 from
PubChem "2-(1h-Benzotriazole-1-yl)-1...
-
during SPPS,
though the
approach was
regarded as 'costly and tedious'.
BOP PyBOP Li, Haitao; Jiang, Xiao****; Ye, Yun-hua; Fan, Chongxu; Romoff, Todd; Goodman...
-
tautomerizable heterocycle is
activated with a
phosphonium salt (
PyBroP,
PyBOP, BroP, or
BOP), and
subsequent functionalization with
either a nucleophile...
-
amide Retosiban 8 by
activating the acid with the
peptide coupling reagent PyBOP (benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate) followed...
- Biochemistry. 36 (7): 1836–45. doi:10.1021/bi962476u. PMID 9048568. Kwok
PY,
Muellner FW,
Fried J (June 1987). "Enzymatic
conversions of 10,10-difluoroarachidonic...