-
Proneural genes encode transcription factors of the
basic helix-loop-helix (bHLH)
class which are
responsible for the
development of
neuroectodermal progenitor...
-
signaling from the MDO
induces a posterior-to-anterior wave of
expression the
proneural gene Neurogenin1 in the
major (caudal) part of the thalamus, and Ascl1...
-
neuroblast fate, the
genes of the AS-C are
called proneural genes. However, the AS-C has non-
proneural functions, such as
specifying muscle and gut progenitors...
- seen in the
classical subtype alongside chromosome 7 amplification. The
proneural subtype often has high
rates of
alterations in TP53 (p53), and in PDGFRA...
-
codeletion and the
expression of
proneural genes,
suggesting that
gliomas with a 1p19q
codeletion represent a
subgroup of
proneural gliomas. Oligodendrogliomas...
-
homologous Btg2 gene. This
protein controls cell
cycle progression and
proneural genes expression by
acting as a
transcription coregulator that enhances...
-
environmental cues.
Interaction with
other transcription factors, such as
proneural factors and
Notch signaling,
further refines the
neurogenic cascades....
- PMID 20978236. S2CID 38362848. Huang, C; Chan, JA; Schuurmans, C (2014). "
Proneural bHLH
Genes in
Development and Disease". BHLH
Transcription Factors in...
-
Zordan P,
Croci L,
Hawkes R,
Consalez GG (2008). "Comparative
analysis of
proneural gene
expression in the
embryonic cerebellum". Dev Dyn. 237 (6): 726–735...
-
Kucerova R,
Philpott A (October 2010). "Non-canonical
ubiquitylation of the
proneural protein Ngn2
occurs in both
Xenopus embryos and
mammalian cells". Biochemical...
