-
amino acids glycine and proline. This is the
collagen precursor procollagen. Then,
procollagen is
modified by the
addition of
hydroxyl groups to the amino...
-
cells as a pre-
procollagen. The
signal peptide is
cleaved off
producing a
procollagen molecule.
Three identical type III
procollagen chains come together...
-
Procollagen-proline dioxygenase,
commonly known as
prolyl hydroxylase, is a
member of the
class of
enzymes known as alpha-ketoglutarate-dependent hydroxylases...
-
modifications in
order to make the
final type I
collagen product. The
procollagen complex is then
modified by
different enzyme proteinases which cleave...
-
knowledge of cell life cycle.
Procollagen is
studied because it
plays a role in
diseases related to
connective tissues.
Procollagen interacts with collagen...
- peptidase,
aminoterminal procollagen peptidase,
procollagen aminoterminal protease,
procollagen N-terminal proteinase, type I/II
procollagen N-proteinase, type...
- Type II
collagen is the
basis for
hyaline cartilage,
including the
articular cartilages at
joint surfaces. It is
formed by
homotrimers of collagen, type...
-
Lysyl hydroxylases (or
procollagen-lysine 5-dioxygenases) are alpha-ketoglutarate-dependent
hydroxylases enzymes that
catalyze the
hydroxylation of lysine...
- C-terminal peptidase,
procollagen C-proteinase,
procollagen carboxypeptidase,
procollagen carboxy-terminal proteinase,
procollagen peptidase) is an enzyme...
- deficiency) –
defect in
collagen synthesis due to lack of
hydroxylation of
procollagen results in
weakened capillary walls and
cells Meningococcemia Clumping...
