-
steroids stemming from 5α-
pregnane (originally allopregnane) and 5β-
pregnane (17β-ethyletiocholane). It has a
gonane core. 5β-
Pregnane is the
parent of pregnanediones...
-
virilization of the male fetus.
Allopregnanolone is an
endogenous inhibitory pregnane neurosteroid. It is made from pregnenolone, and is a
positive allosteric...
- In the
field of
molecular biology, the
pregnane X
receptor (PXR), also
known as the
steroid and
xenobiotic sensing nuclear receptor (SXR) or
nuclear receptor...
- 5α-Dihydroprogesterone (5α-DHP, allopregnanedione, or 5α-
pregnane-3,20-dione) is an
endogenous progestogen and
neurosteroid that is
synthesized from progesterone...
- 5α-
Pregnane-3α,17α-diol-20-one, also
known as 17α-hydroxyallopregnanolone (17-OH-allo) is an
endogenous steroid. 5α-
Pregnane-3α,17α-diol-20-one is a metabolite...
- derivatives. It is one of the
epimers of
pregnane, the
other being 5α-
pregnane.
Derivatives of 5β-
pregnane include the
naturally occurring steroids...
-
serves as a skeleton.
These parent structures have
specific names, such as
pregnane, androstane, etc. The
derivatives carry various functional groups called...
- allopregnanedione): 5α-
pregnane-3,20-dione –
GABAA receptor positive allosteric modulator 5β-Dihydroprogesterone (5β-DHP; pregnanedione): 5β-
pregnane-3,20-dione –...
-
progestogens are
characterized by
their basic 21-carbon skeleton,
called a
pregnane skeleton (C21). In
similar manner, the
estrogens possess an
estrane skeleton...
- 5β-Dihydroprogesterone (5β-DHP, pregnanedione, or 5β-
pregnane-3,20-dione) is an
endogenous neurosteroid and an
intermediate in the
biosynthesis of pregnanolone...
