-
Allopregnanolone is a
naturally occurring neurosteroid which is made in the body from the
hormone progesterone. As a medication,
allopregnanolone is referred...
- injury. Ganaxolone, a
synthetic analog of the
endogenous neurosteroid allopregnanolone, is
under investigation for the
treatment of epilepsy.
Based on differences...
- from progesterone. It is also an
intermediate in the
synthesis of
allopregnanolone and
isopregnanolone from progesterone. 5α-DHP is
metabolized by the...
- is
produced in the body from progesterone. It is
closely related to
allopregnanolone,
which has
similar properties.
Pregnanolone is a
positive allosteric...
- 5α-THP), is an
endogenous neurosteroid and a
natural 3β-epimer of
allopregnanolone. It has been
reported to act as a subunit-selective
negative allosteric...
- include:
Progestogens Pregnenolone →
Progesterone →
Allopregnanedione →
Allopregnanolone 17α-Hydroxypregnenolone → 17α-Hydroxyprogesterone
Androgens Dehydroepiandrosterone...
- a
precursor for
other neurosteroids such as
pregnenolone sulfate,
allopregnanolone, and
pregnanolone and for
steroid hormones.
Pregnenolone has low bioavailability...
-
Kavalactones (found in kava)
Loreclezole Neuroactive steroids (e.g.,
allopregnanolone, ganaxolone)
Nonbenzodiazepines (e.g., zaleplon, zolpidem, zopiclone...
-
inhibits the
production of
several anticonvulsant neurosteroids including allopregnanolone, androstanediol, and THDOC.
Adverse effects from
finasteride are rare;...
-
variant forms 'Allo, a form of ****o Allo, a
shortening of allo****ual
Allopregnanolone, a
neurosteroid sometimes abbreviated as "ALLO" 'Allo 'Allo!, a British...
