-
Pitolisant, sold
under the
brand name
Wakix among others, is a
medication used for the
treatment of
excessive daytime sleepiness in
adults with narcolepsy...
- the brain.
Pitolisant is an
histamine 3 (H3)-receptor
inverse agonist. As
histamine 3 (H3)
receptors mainly act as autoreceptors,
pitolisant decreases...
- clobenpropit, ABT-239, ciproxifan, conessine, A-349,821, betahistine, and
pitolisant. The
histamine H3
receptor (H3R) was
discovered in 1983 and was one of...
-
which acts as a norepinephrine–dopamine
reuptake inhibitor (NDRI), and
pitolisant,
which acts as a
histamine 3 (H3)
receptor antagonist/inverse agonist...
-
histamine release in hypothalamus. An
inverse agonist of the
histamine H3 is
Pitolisant.
Results after testing on
animals have
indicated increased wakefulness...
-
conditions such as long QT syndrome, by
certain medications such as
sotalol or
pitolisant, by
disturbances in the
concentrations of
certain salts within the blood...
-
cataplexy in adults:
pitolisant".
National Institute of
Health and Care
Excellence (NICE). 14
March 2017. S**** YY (September 2016). "
Pitolisant:
First Global...
- 2011). "The
histamine H3 receptor: from
discovery to
clinical trials with
pitolisant".
British Journal of Pharmacology. 163 (4): 713–21. doi:10.1111/j.1476-5381...
- agonists:
Loratadine Histamine 3 (H3)
receptor antagonists/inverse agonists:
Pitolisant SERM (selective
estrogen receptor modulators)
Raloxifene Vasodilators...
- (nCPAP)
Therapy (0249-015). http://ClinicalTrials.gov/show/NCT00620659
Pitolisant to ****ess W****ly
Frequency of
Cataplexy Attacks and EDS in Narcoleptic...
