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Paxillin is a
protein that in
humans is
encoded by the PXN gene.
Paxillin is
expressed at
focal adhesions of non-striated
cells and at
costameres of striated...
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phosphorylation site,
while the tail
region contains binding sites for F-actin,
paxillin, and lipids. Essentially,
there is an 835
amino acid N-terminal head, which...
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components of
focal adhesions include actin, filamin, vinculin, talin,
paxillin,
tensin and RSU-1. FAK is
phosphorylated in
response to
integrin engagement...
- motifs. This
group is
limited to
three different adaptor proteins: zyxin,
paxillin, and PINCH. They each
respectively have
different number of LIM domains...
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multocida toxin, a
potent intracellularly acting mitogen,
induces p125FAK and
paxillin tyrosine phosphorylation,
actin stress fiber formation, and
focal contact...
-
hematopoietic cells and is most
homologous to the
focal adhesion protein,
paxillin. It may
function in cell type-specific
signaling by ****ociating with PYK2...
- factor.
PTPrho also
dephosphorylates paxillin on
tyrosine 88.
Higher levels of
tyrosine 88
phosphorylation of
paxillin are
observed in
colon cancers. When...
- (integrins) and
signaling proteins (adhesion
kinase (FAK), talin, vinculin,
paxillin, α-actinin,
GTPases etc.)
which cause changes in cell
shape and actomyosin...
-
phosphorylation of
specific tyrosine residues on the
focal adhesion adapter protein-
paxillin by
specific tyrosine kinases has been
demonstrated to be
essential to force...
- Leucine-Aspartate (LD)-repeat
motif peptides in the
related focal adhesion proteins paxillin (PXN),
leupaxin (LPXN) and TGFB1I1/Hic-5. FAT
domains with a
similar 4-helix...
