- β-trans-bergamotene is a
precursor in the
biosynthesis of fumagillin,
ovalicin, and
related antibiotics. "Metabocard for alpha-Bergamotene (HMDB0036678)"...
- give 2S-hydroxymutilin
after hydrolysis of the
silyl protecting groups.
Ovalicin, fumagillin, and
their derivatives exhibit strong anti-angiogenesis properties...
- and
diastereoselective total syntheses of fumagillol, RK-805, FR65814,
ovalicin, and 5-demethylovalicin".
Angewandte Chemie. 45 (5): 789–793. doi:10.1002/anie...
- can
trigger P.
ovale to
produce ovalicin as a response. Past
studies have
demonstrated the
potential for
ovalicin as a
tumour suppressing drug, as it...
- is also the
target of two
groups of anti-angiogenic
natural products,
ovalicin and fumagillin, and
their analogs such as beloranib. In
living organisms...
- Crews, and
Raymond Deshaies in 2001. A
chimeric molecule consisting of
ovalicin (a MetAP-2
small molecule inhibitor) and IκBα
phosphopeptide (a recruiter...
- used a
similar screen to
discover the
nonmyelotoxic immunosuppressant ovalicin.
Applying the
revised screen led to the
discovery of the
potent biological...
-
derivative 2gz5:
Human Type 1
methionine aminopeptidase in
complex with
ovalicin at 1.1 Ang 2nq6:
Crystal structure of
human methionine aminopeptidase type...
