-
nucleophilic substitution by lower-order
organocuprates depends in a
profound way on the
structure of the substrate,
organocuprate, and
reaction conditions. Early...
-
compounds fact
sheet J. F.
Normant (1972). "Organocopper(I)
Compounds and
Organocuprates in Synthesis". Synthesis. 1972 (2): 63–80. doi:10.1055/s-1972-21833...
-
usefully modified in the
present of
other metals. Copper(I)
salts give
organocuprates that
preferentially effect 1,4 addition.
Cerium trichloride allows selective...
- 1021/ja067533d. PMID 17506552. Hu, Haipeng; Snyder,
James P. (2007). "
Organocuprate Conjugate Addition: The Square-Planar "CuIII" Intermediate". Journal...
-
regeneration of
unsaturation following 1,4-addition with
nucleophiles such as
organocuprates. For
acyclic substrates the
reaction yields the
thermodynamic E-olefin...
-
inhibitors of 2,3-oxidosqualene-lanosterol cyclase:
conjugate addition of
organocuprates to N-(carbobenzyloxy)-3-carbomethoxy-5,6-dihydro-4-pyridone". Journal...
-
immediate use,
including zinc–copper
couple and zinc/silver couples. and
organocuprates Monohalo ketones are
reduced by both one-electron and two-electron reducing...
-
reacting alkyl lithium species with copper(I) halide. The
resulting organocuprates are
generally less
reactive toward aldehydes and
ketones than organolithium...
-
reagents to alpha,beta-unsaturated
ketones led to the
development of
organocuprate reagents that are
widely used
today in
organic synthesis: This finding...
- cyclizations.
Carbon nucleophiles such as
organolithium reagents and
organocuprates are also effective. One
application of a ring-opening
reaction in asymmetric...
