- can act as
nucleophiles.
Because nucleophiles donate electrons, they are
Lewis bases.
Nucleophilic describes the
affinity of a
nucleophile to bond with...
-
broadened to
include nucleophiles other than enolates. Some
examples of
nucleophiles include doubly stabilized carbon nucleophiles such as beta-ketoesters...
-
reaction of the
ester p-nitrophenyl
acetate with a
range of
nucleophiles.
Regular nucleophiles such as the
fluoride anion, aniline, pyridine,
ethylene diamine...
-
Nucleophilic substitution reactions are
common in
organic chemistry.
Nucleophiles often attack a
saturated aliphatic carbon. Less often, they may attack...
- than as a
nucleophile,
abstracting a
proton and
leading to
formation of the alkene. This
pathway is
favored with
sterically hindered nucleophiles. Elimination...
- reactions.
Embedding the
nucleophile in a
triad increases its
reactivity for
efficient catalysis. The most
commonly used
nucleophiles are the
hydroxyl (OH)...
- the
group donating electron pairs.
Nucleophilic addition reactions of
nucleophiles with
electrophilic double or
triple bond (π bonds)
create a new carbon...
- "soft"
nucleophiles using a
paradigm for
describing nucleophiles that
largely rests on the pKas of
their conjugate acids. "Hard"
nucleophiles typically...
-
polar protic solvents include water and alcohols,
which will also act as
nucleophiles, and the
process is
known as solvolysis. The Y
scale correlates solvolysis...
- to the
polar nature of the C−Li bond,
organolithium reagents are good
nucleophiles and
strong bases. For
laboratory organic synthesis, many organolithium...
