- interactions.
Further modifications on N-
myristoylated proteins can add
another level of
regulation for
myristoylated protein. Dual
acylation can facilitate...
- vertebrates. Src
family kinases contain six
conserved domains: a N-terminal
myristoylated segment, a SH2 domain, a SH3 domain, a
linker region, a
tyrosine kinase...
-
Myristoylated alanine-rich C-kinase
substrate is a
protein that in
humans is
encoded by the
MARCKS gene. It
plays important roles in cell shape, cell...
- wild-type ABL has a
myristoylated N-terminus,
which binds to an
allosteric site, but the ABL
fusion protein does not have the
myristoylated domain. In the...
- "Fatty
acylation of proteins: New
insights into
membrane targeting of
myristoylated and
palmitoylated proteins".
Biochimica et
Biophysica Acta (BBA) - Molecular...
- lipidated, that is,
covalently modified with
lipid extensions. They may be
myristoylated,
palmitoylated or prenylated.
Hurowitz EH,
Melnyk JM, Chen YJ, Kouros-Mehr...
- cell
division (i.e. cancer). This is due to the
replacement of the
myristoylated cap region,
which when
present induces a
conformational change rendering...
-
either a
serine or
threonine at
position 5.
Proteins that have been
myristoylated are
involved in
signal transduction cascade, protein-protein interactions...
-
binds to the
cytosolic side of the cis-Golgi
membrane and
inserts the
myristoylated N-terminal
amphipathic alpha-helix into the membrane.
Membrane proteins:...
-
basic and
aromatic residues to
bilayer membranes:
phenylalanine in the
myristoylated alanine-rich C
kinase substrate effector domain penetrates into the...
