Definition of Lepirudin. Meaning of Lepirudin. Synonyms of Lepirudin

- Lepirudin is an anticoagulant that functions as a direct thrombin inhibitor. Brand name: Refludan, Generic: Lepirudin rDNA for injection. Lepirudin is...
- may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared). Argatroban...
- with genetic engineering. It is now available in a recombinant form as lepirudin (Refludan) and desirudin (Revasc, Iprivask). Development of other DTIs...
- inhibitor. Current members of this class include the bivalent drugs hirudin, lepirudin, and bivalirudin and the monovalent drugs argatroban and dabigatran. An...
- needed] According to a systematic review, people with HIT treated with lepirudin showed a relative risk reduction of clinical outcome (death, am****tion...
- thrombosis. Treatment may include a direct thrombin inhibitor, such as lepirudin or argatroban. Other "blood thinners" sometimes used in this setting include...
- including: recombinant hirudin derived from Hansenula (Thrombexx, Extrauma) lepirudin (Refludan) – differs by one amino acid substitution and removal of sulfate...
- Karl-Georg; Van de Loo, Andreas; Bohler, Joachim (1999). "Recombinant hirudin (lepirudin) as anticoagulant in intensive care patients treated with continuous hemodialysis"...
- September 2006. Fabrizio MC (2001). "Use of Ecarin Clotting Time (ECT) with Lepirudin Therapy in Heparin-Induced Thrombocytopenia and Cardiopulmonary Byp****"...
- under development; some members are already in clinical use (such as lepirudin). Also in clinical use are other small molecular compounds that interfere...