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Iodothyronine deiodinases (EC 1.21.99.4 and EC 1.21.99.3) are a
subfamily of
deiodinase enzymes important in the
activation and
deactivation of thyroid...
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phospholipid bilayers of
target cells,
instead relying on
transmembrane iodothyronine transporters. The
lipophilicity of T3 and T4
requires their binding...
-
instar stages in
hemimetabolous insects. In chordates,
metamorphosis is
iodothyronine-induced and an
ancestral feature of all chordates. All
three categories...
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Thyroxine 5-deiodinase also
known as type III
iodothyronine deiodinase (EC
number 1.21.99.3) is an
enzyme that in
humans is
encoded by the DIO3 gene....
- triiodothyronine. The T4 → T3
conversion is
mediated by the
selenoenzyme iodothyronine deiodinase. T3-thyroxine is a
unique example of an
iodine compound that...
- or
deactivation of
thyroid hormones.
Types of
deiodinases include:
Iodothyronine deiodinases catalyze release of
iodine directly from the
thyronine hormones...
- main
thyroid hormone T3. T4 is
converted as
required in the
tissues by
iodothyronine deiodinase.
Deficiency of
deiodinase can
mimic hypothyroidism due to...
- (3,5,3′ triiodothyronine, T3).
Reverse T3 is the third-most
common iodothyronine the
thyroid gland releases into the bloodstream, at 0.9%; tetraiodothyronine...
- Type II
iodothyronine deiodinase (
iodothyronine 5'-deiodinase,
iodothyronine 5'-monodeiodinase) is an
enzyme that in
humans is
encoded by the DIO2 gene...
- 3,3'-Diiodothyronine, also
known as 3,3'-T2, is a
metabolite of
thyroid hormone. It is
formed from the
breakdown of triiodothyronine.
Levels can be affected...
