Definition of Inflammasome. Meaning of Inflammasome. Synonyms of Inflammasome

- Inflammasomes are cytosolic multiprotein complexes of the innate immune system responsible for the activation of inflammatory responses and cell death...
- is expressed predominantly in macrophages and as a component of the inflammasome,: 436  detects products of damaged cells such as extracellular ATP and...
- leucine-rich repeat and pyrin domain containing receptor 3) inflammasome. An inflammasome can be defined as an immune system receptor that induces inflammation...
- multiprotein complexes called inflammasomes in response to certain infections. In healthy individuals, pyrin-mediated inflammasome ****embly (which leads to...
- immune activation and, in the case of inflammasome disorders, are attributable to activation of an inflammasome complex nucleated by innate immune sensors...
- supramolecular complex termed the inflammasome (also known as a pyroptosome) upon intracellular danger signals. The inflammasome activates a different set of...
- several factors. Over-activation of the inflammasome is one mechanism contributing to inflammaging. The inflammasome is a multi-protein complex consisting...
- joints, or skin are signs of familial Mediterranean fever. Pyrin forms an inflammasome which senses RhoA GTPases inactivation and subsequent kinases (PKN1 and...
- normally present in the inflammasome. The mutated pyrin protein is thought to cause inappropriate activation of the inflammasome, leading to release of...
- canonical pathway and is activated by canonical inflammasomes such as NLRP3 and NLRC4 inflammasomes, which are multi-protein complexes that are formed...