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Indolamines are a
family of
neurotransmitters that
share a
common molecular structure.
Indolamines are a
classification of
monoamine neurotransmitter,...
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Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO EC 1.13.11.52) is a heme-containing
enzyme physiologically expressed in a
number of
tissues and cells...
- Melatonin, an
indoleamine, is a
natural compound produced by
various organisms,
including bacteria and eukaryotes. Its
discovery in 1958 by
Aaron B. Lerner...
- in
platelets and
surrounding tissue. Biochemically,
serotonin is an
indoleamine synthesized from
tryptophan and
metabolized primarily in the
liver to...
-
Neethling AC,
Shanley BC (September 1976). "Enzymatic N-methylation of
indoleamines by
mammalian brain: fact or artefact?".
Journal of Neurochemistry. 27...
- (September 2011). "Multiple
receptors contribute to the
behavioral effects of
indoleamine hallucinogens". Neuropharmacology. 61 (3): 364–381. doi:10.1016/j.neuropharm...
- (September 2011). "Multiple
receptors contribute to the
behavioral effects of
indoleamine hallucinogens". Neuropharmacology. 61 (3): 364–381. doi:10.1016/j.neuropharm...
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arthritis under the
brand name Olumiant. As of 2016 epacadostat, an
indoleamine 2,3-dioxygenase (IDO1) inhibitor, was in
development for
various cancers...
-
known as 4-phosphoryloxy-N,N,N-trimethyltryptamine (4-PO-TMT), is an
indoleamine derivative which occurs naturally within the
mushrooms Inocybe aeruginascens...
- is an
investigational drug for cancer.
Epacadostat is an
inhibitor of
indoleamine 2,3-dioxygenase-1 (IDO1).
Epacadostat inhibits IDO1 by competitively...