-
phenylmethylsulfonyl fluoride (PMSF) is a
serine protease inhibitor (serine
hydrolase inactivator)
commonly used in the
preparation of cell lysates. PMSF does not inactivate...
- CYP2D6
metabolizes metoclopramide, a
reversible inhibitor, but not
inactivator, of CYP2D6. The
major metabolites of
metoclopramide are N-hydroxylation...
- and
Tourette syndrome. CPP-115 is a GABA
aminotransferase (GABA-AT)
inactivator. CPP-115 was
discovered in the
research laboratory of
Richard B. Silverman...
-
Plasmin is an
important enzyme (EC 3.4.21.7)
present in
blood that
degrades many
blood plasma proteins,
including fibrin clots. The
degradation of fibrin...
-
protein and C3b
inactivator control the C3
convertase of the
classical pathway in a
similar way to that
described for β1H and C3b
inactivator in the alternative...
- in
humans or animals. Additionally,
methysticin is a mechanism-based
inactivator of CYP2C9,
irreversibly inhibiting the
enzyme through NADPH-dependent...
- C1-inhibitor (C1-inh, C1
esterase inhibitor) is a
protease inhibitor belonging to the
serpin superfamily. Its main
function is the
inhibition of the complement...
- the
active site. As such, it is
sometimes referred to as a “suicide
inactivator” of MAO. It was
invented by
Bruce Horrom of
Abbott in the 1960s by structure...
-
Schreiber RD, Müller-Eberhard HJ (July 1977). "Human
complement C3b
inactivator: isolation, characterization, and
demonstration of an
absolute requirement...
- Synaptosomal-****ociated
protein 25
inactivators:
Botulinum toxin (A, C, E)
VAMPTooltip Vesicle-****ociated
membrane protein inactivators:
Botulinum toxin (B, D, F...
