-
Statins (or HMG-CoA
reductase inhibitors) are a
class of
medications that
lower cholesterol. They are
prescribed typically to
people who are at high risk...
- In biochemistry,
hydroxymethylglutaryl-CoA
synthase or HMG-CoA
synthase EC 2.3.3.10 is an
enzyme which catalyzes the
reaction in
which acetyl-CoA condenses...
- 5' AMP-activated
protein kinase or AMPK or 5'
adenosine monophosphate-activated
protein kinase is an
enzyme (EC 2.7.11.31) that
plays a role in cellular...
- 3-Hydroxy-3-methylglutaryl-CoA
lyase deficiency, (HMGCLD) also
known as
HMGCL deficiency, HMG-CoA
lyase deficiency, or
hydroxymethylglutaric aciduria,...
- β-Hydroxy β-methylglutaryl-CoA (HMG-CoA), also
known as 3-hydroxy-3-methylglutaryl
coenzyme A, is an
intermediate in the
mevalonate and
ketogenesis pathways...
- In enzymology, a
hydroxymethylglutaryl-CoA
reductase (NADPH) (EC 1.1.1.34) is an
enzyme that
catalyzes the
chemical reaction (R)-mevalonate + CoA + 2...
-
among young patients and women.
Statins work by
inhibiting HMG-CoA (
hydroxymethylglutaryl-coenzyme A) reductase, a
hepatic rate-limiting
enzyme in cholesterol's...
- + dephospho-{[
hydroxymethylglutaryl-CoA
reductase (NADPH)] kinase} ⇌ {\displaystyle \rightleftharpoons } ADP + {[
hydroxymethylglutaryl-CoA
reductase (NADPH)]...
-
Robert MF,
Elsliger MA, Mitc**** GA (1996). "Characterization of the
hydroxymethylglutaryl-CoA
lyase precursor, a
protein targeted to
peroxisomes and mitochondria"...
- The
enzyme [
hydroxymethylglutaryl-CoA
reductase (NADPH)]-phosphatase (EC 3.1.3.47)
catalyzes the
reaction [
hydroxymethylglutaryl-CoA
reductase (NADPH)]...