-
recurring limitation to
these hydroxamates (Prinomastat in particular) is drug
metabolism including loss of the
hydroxamate zinc-binding group.
These inhibitors...
-
major groups of siderop****s
include the
catecholates (phenolates),
hydroxamates and
carboxylates (e.g.
derivatives of
citric acid).
Citric acid can also...
-
chloroformates and phosgene,
carbonate esters, thioesters, lactones, lactams,
hydroxamates, and isocyanates.
Examples of
inorganic carbonyl compounds are carbon...
-
conjugated O,O
chelating ligand. Many
hydroxamic acids and many iron
hydroxamates have been
isolated from
natural sources. They
function as ligands, usually...
- atom at the MMP
active site tightly.
Common chelating groups include hydroxamates, carboxylates, thiols, and phosphinyls.
Hydroxymates are particularly...
- The
Lossen rearrangement is the
conversion of a
hydroxamate ester to an isocyanate.
Typically O-acyl, sulfonyl, or
phosphoryl O-derivative are emplo****...
-
transporter BtuB, Fe(III)-pyochelin
receptor FptA,
receptor FepA,
ferric hydroxamate uptake receptor FhuA,
transporter FecA, and
pyoverdine receptor FpvA...
-
Vanhaecke T,
Papeleu P,
Elaut G,
Rogiers V (2004). "Trichostatin A-like
hydroxamate histone deacetylase inhibitors as
therapeutic agents:
toxicological point...
- post-exposure, to
inhibition by
protease inhibitors, e.g., zinc-coordinating
hydroxamates. University-based
ophthalmologists in the US and
Canada further refined...
-
order of the
typical zinc
binding affinity were:
hydroxamic acids (or
hydroxamates), such as
trichostatin A,
cyclic tetrapeptides (such as
trapoxin B, and...
