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Homogentisate 1,2-dioxygenase (homogentisic acid oxidase,
homogentisate oxidase, homogentisicase) is an
enzyme which catalyzes the
conversion of homogentisate...
- 4-hydroxyphenylpyruvate
dioxygenase to
yield homogentisate. If
active and present, the
enzyme homogentisate 1,2-dioxygenase
further degrades homogentisic...
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disease which is
caused by a
mutation in the HGD gene for the
enzyme homogentisate 1,2-dioxygenase (EC 1.13.11.5); if a
person inherits an
abnormal copy...
-
catabolism of
tyrosine - the
conversion of 4-hydroxyphenylpyruvate into
homogentisate. HPPD also
catalyzes the
conversion of
phenylpyruvate to 2-hydroxyphenylacetate...
- off CO2
homogentisate (2,5-dihydroxyphenyl-1-acetate). In
order to
split the
aromatic ring of
homogentisate, a
further dioxygenase,
homogentisate 1,2-dioxygenase...
- autosomal-recessive disease,
known as alkaptonuria, that is
caused by a lack of
homogentisate oxidase enzyme.
Exogenous ochronosis is an
avoidable dermatitis that...
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solanesyl diphosphate is
synthesized through the MEP/DOXP pathway.
Homogentisate is
formed from p-hydroxyphenylpyruvate and is then
combined with solanesyl...
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healthy body, the
production of
pyomelanin is
blocked by the
enzyme homogentisate 1,2-dioxygenase
which prevents the ac****ulation of HGA.
Pyomelanin can...
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pyridafol and credazine.
Cyclopyrimorate works by a
novel target site, of
homogentisate solanesyltransferase (HST). The new
mechanism avoids resistance to acetolactate...
-
inborn error of
metabolism caused by
mutations in the HGO gene and
homogentisate 1,2-dioxygenase deficiency.
Pseudoxanthoma elasti**** - rare multisystem...
