- The
FKBPs, or FK506
binding proteins,
constitute a
family of
proteins that have
prolyl isomerase activity and are
related to the
cyclophilins in function...
- organisms;
these DFIs are
natural chimera of CyP and
FKBPs,
fused in
either order (CyP-
FKBP or
FKBP-CyP).
Immunophilins act as
receptors for immunosuppressive...
- It is also
commonly referred to as
FKBP-12 or FKBP12 and is a
member of a
family of FK506-binding
proteins (
FKBPs). The
protein encoded by this gene is...
- conditions.
Proteins with
prolyl isomerase activity include cyclophilin,
FKBPs, and parvulin,
although larger proteins can also
contain prolyl isomerase...
- 1 (mTORC1). mTOR has also been
called FRAP (
FKBP-rapamycin-****ociated protein), RAFT (rapamycin and
FKBP target), RAPT1, or SEP. The
earlier names FRAP...
- TORC2 complex.
Plant species have TOR
proteins in the
protein kinase and
FKBP-rapamycin
binding (FRB)
domains that
share a
similar amino acid sequence...
- split-Cas9
system developed by
fusing two
constructs of split-Cas9 with FRB and
FKBP fragments.
Other studies have been able to
induce transcription of Cas9 with...
-
derivative of the drug
tacrolimus (FK506), to
induce homo-dimerization of
FKBP. This
system was used in vivo to
induce binding between cell
surface receptors...
-
proteins as impurities. In E. coli for instance, a
prominent example is
FKBP-type
peptidyl prolyl isomerase,
which appears around 25 kDa on SDS-PAGE....
- gene
clusters named fkb. The 19
genes are fkbQ, fkbN, fkbM, fkbD, fkbA,
fkbP, fkbO, fkbB, fkbC, fkbL, fkbK, fkbJ, fkbI, fkbH, fkbG, allD, allR, allK and...
