- (S)-propranolol is 130
times more
active than its (R)-enantiomer. The
eutomer is the
enantiomer having the
desired pharmacological activity, e.g., as...
-
chiral center and
exists as a pair of enantiomers. (S)-Ibuprofen, the
eutomer, is
responsible for the
desired therapeutic effect. The
inactive (R)-enantiomer...
- been coined,
eutomer and distomer. The
member of the
chiral twin that has
greater physiological activity is
referred to as the
eutomer and the other...
- racemase,
converts (R)-ibuprofen into the (S)-enantiomer. (S)-ibuprofen, the
eutomer,
harbors the
desired therapeutic activity. The
inactive (R)-enantiomer...
- is
essentially a
chiral switch of (±)-cetirizine. This enantiomer, the
eutomer, is more
selective and the (S)-counterpart, the distomer, is inactive....
-
metabolism status.
AstraZeneca also
developed esomeprazole (Nexium)
which is a
eutomer,
purely the (S)-enantiomer,
rather than a
racemate like omeprazole. Omeprazole...
- ketoprofen, fenoprofen, benoxaprophen, etc. For this group, only S-enantiomer (
eutomer) is
active i.e. has analgesic and anti-inflammatory effect. In the body...
- but
entirely different effects. The
desired enantiomer is
known as an
eutomer while the
undesired enantiomer is
known as the distomer. When
equal amounts...
-
Arpraziquantel ((R)-praziquantel) is the
eutomer (the
biologically active enantiomer) of praziquantel, and is a
medication which is
currently under investigation...
- been coined:
eutomer and distomer. The
member of the
chiral twin that has
greater physiological activity is
referred to as the
eutomer and the other...
