-
pathway consists of a
large number of metabolite-forming CYP
epoxygenases and the
human epoxygenases have
important differences from
those of
animal models...
- by the CYP
epoxygenases, some of
which differ in activities; 3) the
diversity of
fatty acid
substrates metabolized by the CYP
epoxygenases some of which...
- 9-oxo-octadecdienoic acid.
Certain cytochrome P450 enzymes, the CYP
epoxygenases,
catalyze oxidation of LA to
epoxide products viz., its 12,13-epoxide...
- conditions. ALOXE3
preferentially metabolizes arachidonic acid to hepoxilins.
Epoxygenases:
these are
cytochrome P450
enzymes which generate nonclassic eicosanoid...
-
Meyer UA, Visvikis-Siest S (November 2014). "Human
cytochrome P450
epoxygenases:
variability in
expression and role in inflammation-related disorders"...
-
metabolizes important endogenous compounds such as
serotonin and,
owing to its
epoxygenase activity,
various polyunsaturated fatty acids,
converting these fatty...
-
Capdevila parti****ted in the
identification of
roles for: a) the Cyp2c44
Epoxygenases and the EETs in
tumor vascularization and
progression in
rodent models...
-
polyunsaturated fatty acids that are made by
various cytochrome P450
epoxygenases. EETs, EDPs, and EEQs have
various effects in
animals including vasodilation...
-
their toxic forms (see
table below for examples). CYP3A4 also
possesses epoxygenase activity in that it
metabolizes arachidonic acid to epoxyeicosatrienoic...
- (January 2013). "Cytochrome P4502S1: a
novel monocyte/macrophage
fatty acid
epoxygenase in
human atherosclerotic plaques".
Basic Research in Cardiology. 108...
