-
pharmacological activity, e.g., as an
active ingredient in a drug. The
distomer, on the
other hand, is the
enantiomer of the
eutomer which may have undesired...
-
responsible for the
desired therapeutic effect. The
inactive (R)-enantiomer, the
distomer,
undergoes a
unidirectional chiral inversion to give the
active (S)-enantiomer...
- studied. The
eutomer for one
effect may well be the
distomer when
another is studied. The eutomer/
distomer ratio is
called the
eudysmic ratio. The behavior...
-
eutomer and the
other one with
lesser activity is
referred to as
distomer. The eutomer/
distomer ratio is
called the
eudisimic ratio and
reflects the degree...
- enantiomer, the eutomer, is more
selective and the (S)-counterpart, the
distomer, is inactive. Chemically,
levocetirizine is the
active levorotary enantiomer...
- most
other phenethylamines (e.g. MDMA)
where the R-isomer
serves as the
distomer. The
toxicity of DOB is not
fully known,
although high
doses may cause...
-
therapeutic activity. Interestingly, the
inactive (R)-enantiomer, the
distomer,
undergoes a
unidirectional chiral inversion to
offer the
active (S)-enantiomer...
- is
known as an
eutomer while the
undesired enantiomer is
known as the
distomer. When
equal amounts of both
enantiomers are
found in a mixture, the mixture...
-
eutomer is the (6R,10bS) stereoisomer,
known as JNJ-39836966, and the
distomer, (6S,10bR), is JNJ-39836732
There is some
confusion over the nomenclature...
- into the
active S-enantiomer and not vice versa. The “inactive” R-isomer (
distomer) may be
responsible for the
gastrointestinal irritation and
related side-effects...
