-
Desymmetrization in
stereochemistry is the
modification of a
molecule that
results in the loss of one or more
symmetry elements. A
common application of...
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corresponds to a
desymmetrization reaction. For instance,
mevalonolactone may be
synthesized rapidly from a
symmetric diester via
desymmetrizing hydrolysis...
- Jean-Marc; Bressy,
Cyril (May 2017). "Catalytic
Enantioselective Desymmetrization of Meso
Compounds in
Total Synthesis of
Natural Products:
Towards an...
- S. Simpkins, and
Fengzhi Zhang (2007). "Chiral
Lithium Amide Base
Desymmetrization of a Ring
Fused Imide:
Formation of (3aS,7aS)-2[2-(3,4-Dimethoxyphenyl)-ethyl]-1...
- Chênevert R,
Morin P (2009). "Synthesis of (−)-lobeline via
enzymatic desymmetrization of lobelanidine". Bioorg. Med. Chem. 17 (5): 1837–9. doi:10.1016/j...
- Weinheim. doi:10.1002/14356007.a04_455.pub2 Nugent,
William A. (1998). "
Desymmetrization of Meso
Epoxides with Halides: A New
Catalytic Reaction Based on Mechanistic...
-
Wolstenholme D,
Zambon A (May 2007). "Chiral
polycyclic ketones via
desymmetrization of dihaloolefins". The
Journal of
Organic Chemistry. 72 (11): 4272–5...
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catalysts for
asymmetric epoxidation,
hydrolytic kinetic resolution and
desymmetrization of epoxides,
asymmetric pericyclic reactions, and
asymmetric additions...
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three stereoisomers of this
pheromone is
employing lipase-catalyzed
desymmetrization or
enantiomer separation of syn- or anti-2,4-dimethylpentane-1,5-diol...
- synproportionation. More generally, the term can be
applied to any
desymmetrizing reaction where two
molecules of one type
react to give one each of two...
