-
Deamination is the
removal of an
amino group from a molecule.
Enzymes that
catalyse this
reaction are
called deaminases. In the
human body, deamination...
-
Oxidative deamination is a form of
deamination that
generates α-keto
acids and
other oxidized products from amine-containing compounds, and
occurs primarily...
- it is
inherently unstable, and can
change into
uracil (spontaneous
deamination). This can lead to a
point mutation if not
repaired by the DNA repair...
- APOBEC3G
belongs to the
family of
cytidine deaminases that
catalyze the
deamination of
cytidine to
uridine in the
single stranded DNA substrate. The C-terminal...
-
members that
encode mitochondrial enzymes which catalyze the
oxidative deamination of amines, such as norepinephrine,
serotonin and tyramine. A mutation...
- the
breakdown of fat in
adipose tissue to
fatty acids, and
oxidative deamination of
neurotransmitters by
monoamine oxidase.
There are many
signals that...
- high
mutation rate of
methylated CpG sites: the
spontaneously occurring deamination of a
methylated cytosine results in a thymine, and the
resulting G:T...
-
aliphatic alpha- and beta-hydroxylation, N-oxidation, N-dealkylation, and
deamination. The
known metabolic pathways include:
Methamphetamine and amphetamine...
-
located in the
outer mitochondrial membrane. It
catalyzes the
oxidative deamination of
biogenic and
xenobiotic amines and
plays an
important role in the...
- in turn, are
thought to
undergo deamination to
uracil glycol,
dehydration to 5-hydroxycytosine, or both
deamination and
dehydration to 5-hydroxyuracil...
