- in
humans is
encoded by the PTGS2 gene. In
humans it is one of two
cyclooxygenases. It is
involved in the
conversion of
arachidonic acid to prostaglandin...
-
Cyclooxygenase (COX),
officially known as prostaglandin-endoperoxide
synthase (PTGS), is an
enzyme (specifically, a
family of isozymes, EC 1.14.99.1) that...
-
humans is
encoded by the PTGS1 gene. In
humans it is one of two
cyclooxygenases.
Cyclooxygenase (COX) is the
central enzyme in the
biosynthetic pathway to...
-
Cyclooxygenase-2
inhibitors (COX-2 inhibitors), also
known as coxibs, are a type of
nonsteroidal anti-inflammatory drug (NSAID) that
directly target cyclooxygenase-2...
-
following the
sequential oxygenation of
arachidonic acid, DGLA or EPA by
cyclooxygenases (COX-1 and COX-2) and
terminal prostaglandin synthases. The classic...
-
Cyclooxygenase-3 (COX-3) is an
enzyme that is
encoded by the PTGS1 (COX1) gene, but is not
functional in humans. COX-3 is the
third and most
recently discovered...
- PMC 134294. PMID 12427705.
Botting RM (November 2006). "Inhibitors of
cyclooxygenases: mechanisms,
selectivity and uses" (PDF).
Journal of
Physiology and...
- the
third trimester of pregnancy. It
blocks cyclooxygenase-2 (COX-2) more than it
blocks cyclooxygenase-1 (COX-1). It is in the
oxicam family of chemicals...
-
thromboxanes is due to its
irreversible inactivation of the
cyclooxygenase (COX) enzyme.
Cyclooxygenase is
required for
prostaglandin and
thromboxane synthesis...
- part of
pregnancy or
during breastfeeding.
Ketorolac works by
blocking cyclooxygenase 1 and 2 (COX1 and COX2),
thereby decreasing production of prostaglandins...
