-
human alveolar macrophages is
closely related to
liver microsomal carboxylesterases". J. Biol. Chem. 266 (28): 18832–8. doi:10.1016/S0021-9258(18)55139-5...
- JK, Webb EC,
Zerner B (1969). "
Carboxylesterases (EC 3.1.1). A large-scale
purification of pig
liver carboxylesterase". Biochemistry. 8 (5): 2000–6. doi:10...
- is
hydrolyzed into its
active metabolite SN-38 in the
liver by two
carboxylesterase converting enzymes (CES1 and CES2) and in
plasma by butyrylcholinesterase...
- "Cocaethylene
metabolism and
interaction with
cocaine and ethanol: role of
carboxylesterases". Drug
Metabolism and Disposition. 31 (1): 16–20. doi:10.1124/dmd...
-
enzyme has not yet been determined; however, it is
speculated that
carboxylesterases may play a role in
lipid metabolism and/or the blood–brain barrier...
- mino]-carbonyloxycamptothecin, by
human carboxylesterases CES1A1, CES2, and a
newly expressed carboxylesterase isoenzyme, CES3". Drug
Metab Dispos. 32...
-
properties for this application.
Benzil is a
potent inhibitor of
human carboxylesterases,
enzymes involved in the
hydrolysis of
carboxylesters and many clinically...
-
yielding ritalinic acid. The
hydrolysis was
found to be
catalyzed by
carboxylesterase 1 (CES1). Etymologically,
ritalinic acid
shares its
roots with Ritalin...
-
inhibition by organophosphates. The
sequence of a
number of type-B
carboxylesterases indicates that the
majority are
evolutionarily related. As is the...
- the
liver by the
metabolism of
cocaine by hydrolysis,
catalysed by
carboxylesterases, and
subsequently excreted in the urine. It is
readily synthesised...
