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Camptothecins: a
review of
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Pommier Y (2004). "
Camptothecins and...
- needed]
Another drug
class originating from the NCI was the
camptothecins.
Camptothecin,
derived from a
Chinese ornamental tree,
inhibits topoisomerase...
-
antineoplastic drug. It is the
active metabolite of
irinotecan (an
analog of
camptothecin - a
topoisomerase I inhibitor) but has 1000
times more
activity than...
-
Exatecan is a drug
which is a
structural analog of
camptothecin with
antineoplastic activity. A
derivative is used in
Trastuzumab deruxtecan. Abou-Alfa...
- and
stems of C. a****inata
contain the
alkaloid camptothecin.
Several chemical derivatives of
camptothecin are
under investigation for or used as
drugs for...
-
Ixabepilone Entinostat Romidepsin Vorinostat Zabadinostat Belotecan Camptothecin Exatecan Gimatecan Irinotecan Topotecan Etoposide Teniposide Tafluposide...
-
known by its
brand name
Zofran Some
cancer chemotherapy drugs,
including camptothecin derivatives Mirtazapine, a
noradrenergic and
specific serotonergic antidepressant...
- morphine, quinine, and strychnine.
Therapeutically important drugs like
camptothecin (from
Camptotheca a****inata, used in
traditional Chinese medicine) and...
- inhibitors,
irinotecan and topotecan, are semi-synthetically
derived from
camptothecin,
which is
obtained from the
Chinese ornamental tree
Camptotheca a****inata...
