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Camptothecin (CPT) is a
topoisomerase inhibitor. It was
discovered in 1966 by M. E. Wall and M. C. Wani in
systematic screening of
natural products for...
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confer resistance to
camptothecin.
Indenosioquinolines and
indolocarbazoles also lack the
lactone ring
present in
camptothecin,
making them more chemically...
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included on the
World Health Organization's List of
Essential Medicines.
Camptothecin (Fig. 7),
originally derived from the tree
Camptotheca a****inata, targets...
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antineoplastic drug. It is the
active metabolite of
irinotecan (an
analog of
camptothecin - a
topoisomerase I inhibitor) but has 1000
times more
activity than...
- Organization's List of
Essential Medicines. It is made from the
natural compound camptothecin which is
found in the
Chinese ornamental tree
Camptotheca a****inata....
- is a synthetic, water-soluble
analog of the
natural chemical compound camptothecin. It is used in the form of its
hydrochloride salt to
treat ovarian cancer...
- and
stems of C. a****inata
contain the
alkaloid camptothecin.
Several chemical derivatives of
camptothecin are
under investigation for or used as
drugs for...
- name Zofran/
Emiston in BD Some
cancer chemotherapy drugs,
including camptothecin derivatives Mirtazapine, a
noradrenergic and
specific serotonergic antidepressant...
-
Exatecan is a drug
which is a
structural analog of
camptothecin with
antineoplastic activity. A
derivative is used in
Trastuzumab deruxtecan. Abou-Alfa...
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enzyme 8-Cyclopentyl-1,3-dimethylxanthine (8-CPT), a
stimulant drug
Camptothecin, an anti-cancer drug
Certified Personal Trainer, a
personal trainer with...