- of action, most
antimetabolites have high cell
cycle specificity and can
target arrest of
cancer cell DNA replication.
Antimetabolites may also be antibiotics...
- time of more than six months,
antimetabolites may
improve functional and
anatomic results. The use of
antimetabolites had only
minor side effects. Atrophic...
- instituted.
Major categories of drug
interventions include glucocorticoids,
antimetabolites,
biologic agents especially monoclonal anti-tumor
necrosis factor antibodies...
-
Purine analogues are
antimetabolites that
mimic the
structure of
metabolic purines.
Nucleobase analogues Thiopurines such as
thioguanine are used to treat...
-
Pyrimidine analogues are
antimetabolites which mimic the
structure of
metabolic pyrimidines.
Nucleobase analogues Fluorouracil (5FU),
which inhibits thymidylate...
- diseases. High
doses cause pancytopenia and
hemorrhagic cystitis.
Antimetabolites interfere with the
synthesis of
nucleic acids.
These include: folic...
- and vinblastine,
antibiotics such as
bleomycin and dactinomycin, and
antimetabolites such as methotrexate, mercaptopurine, and 5-fluorouracil.
Female infertility...
-
folic acid and is in the
class of
chemotherapy drugs called folate antimetabolites,
which inhibit one or more of
three enzymes that use
folate and derivatives...
-
Antifolates are a
class of
antimetabolite medications that
antagonise (that is, block) the
actions of
folic acid (vitamin B9).
Folic acid's
primary function...
-
Megaloblastic anemia not due to
hypovitaminosis may be
caused by
antimetabolites that
poison DNA
production directly, such as some chemotherapeutic...
