-
Anaphylatoxins, or
complement peptides, are
fragments (C3a, C4a and C5a) that are
produced as part of the
activation of the
complement system. Complement...
- The
anaphylatoxin receptors are a
group of G-protein
coupled receptors which bind
anaphylatoxins.
Members of this
family include: C3a
receptor C3AR1 C5a...
- U.S.
National Library of Medicine.
Gerard C,
Gerard NP (1994). "C5A
anaphylatoxin and its
seven transmembrane-segment receptor".
Annual Review of Immunology...
-
linked by a
disulfide bridge. An
activation peptide, C5a,
which is an
anaphylatoxin that
possesses potent spasmogenic and
chemotactic activity, is derived...
- 1016/0167-4781(95)00209-x. PMID 8605247. Ali H,
Panettieri RA (February 2005). "
Anaphylatoxin C3a
receptors in asthma".
Respiratory Research. 6 (1): 19. doi:10.1186/1465-9921-6-19...
-
cleavage of
complement component 3; the
other is C3b. C3a is a 77
residue anaphylatoxin that
binds to the C3a
receptor (C3aR), a
class A G protein-coupled receptor...
- may
cause local increase of C5a. C5a is a
chemotactic agent and an
anaphylatoxin; it is
essential in the
innate immunity but it is also
linked with the...
- able to more
easily recognize and
engulf pathogen molecules.
While the
anaphylatoxin C3a
interacts with its C3a
receptor (C3aR) to
recruit leukocytes, C3b...
-
usually rapidly cleaved by
carboxypeptidase B. Both C3a and C5a have
anaphylatoxin activity,
directly triggering degranulation of mast
cells as well as...
-
Subsequent investigation demonstrated that complement,
specifically the
anaphylatoxin C5a, can
drive the
Arthus reaction indirectly because the resultant...
