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Anandamide (ANA), also
known as N-arachidonoylethanolamine (AEA), an N-acylethanolamine (NAE), is a
fatty acid neurotransmitter.
Anandamide was the first...
- and are the main
molecular target of the
endogenous partial agonist,
anandamide, as well as
exogenous tetrahydrocannabinol, the most
known active component...
- delta-8-tetrahydrocannabinol (Δ8-THC),
through intracellular CB1 activation,
induce anandamide and 2-arachidonoylglycerol
synthesis produced naturally in the body and...
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established that AM404
increases concentrations of the
endogenous cannabinoid anandamide within the
synaptic cleft,
contributing to its
analgesic activity. This...
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serine hydrolase family of enzymes. It was
first shown to
break down
anandamide (AEA), an N-acylethanolamine (NAE) in 1993. In humans, it is
encoded by...
- a
group of
retrograde neurotransmitters that
include lipids, such as
anandamide and 2-arachidonoylglycerol (2-AG);
plant phytocannabinoids, such as...
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degradatory enzyme for the
endocannabinoid anandamide and, as such,
inhibition of FAAH
leads to an ac****ulation of
anandamide in the CNS and
periphery where it...
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presence of PEA (or
other structurally related N-acylethanolamines)
enhances anandamide activity by an "entourage effect".[non-primary
source needed] Some primary...
- N-acetylphosphatidylethanolamine-hydrolysing
phospholipase D (EC 3.1.4.54, NAPE-PLD,
anandamide-generating
phospholipase D, N-acyl
phosphatidylethanolamine phospholipase...
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enzyme fatty acid
amide hydrolase,
which metabolizes the
endocannabinoid anandamide (AEA).
Activation of the
endocannabinoid system by propofol, possibly...