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Aminoglycoside is a
medicinal and
bacteriologic category of
traditional Gram-negative
antibacterial medications that
inhibit protein synthesis and contain...
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Gentamicin is an
aminoglycoside antibiotic used to
treat several types of
bacterial infections. This may
include bone infections, endocarditis, pelvic...
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injection into a vein
using an IV or into a muscle. Amikacin, like
other aminoglycoside antibiotics, can
cause hearing loss,
balance problems, and
kidney problems...
- Neomycin, also
known as framycetin, is an
aminoglycoside antibiotic that
displays bactericidal activity against Gram-negative
aerobic bacilli and some...
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aminoglycoside-modifying
enzymes and 16S rRNA methyltransferases.
Resistance to
aminoglycosides is
conferred via
numerous mechanisms:
aminoglycoside-modifying...
- In enzymology, an
aminoglycoside N3'-acetyltransferase (EC 2.3.1.81) is an
enzyme that
catalyzes the
chemical reaction acetyl-CoA + a 2-deoxystreptamine...
- In enzymology, an
aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) is an
enzyme that
catalyzes the
chemical reaction acetyl-CoA + kanamycin-B ⇌ {\displaystyle...
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Aminoglycoside-3'-phosphotransferase (APH(3')), also
known as
aminoglycoside kinase, is an
enzyme that
primarily catalyzes the
addition of
phosphate from...
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myasthenia gravis or
other neuromuscular disorders.
Streptomycin is an
aminoglycoside. It
works by
blocking the
ability of 30S
ribosomal subunits to make...
- AAC(6')-Ib:
encodes an
aminoglycoside-modifying
enzyme called aminoglycoside N6'-acetyltransferase,
which alters the
structure of
aminoglycoside antibiotics such...
