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termed trioxilins (TrX's) or
trihydroxyeicoxatrienoic acids (THETA's); HxA3 is
converted to 8,11,12-trihydroxy-5Z,9E,14Z-eicosatrienoic acid (
trioxilin A3...
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trihydroxy products, the
trioxilins. That is,
hepoxilin A3s (8-hydroxy-11,12-oxido-5Z,9E,14Z-eicosatrienoic acid) are
metabolized to
trioxilin A3s (8,11,12-trihydroxy-5Z...
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hepoxilins to
trioxilins has not yet been reported.
Hepoxilins possess several activities (see hepoxilin#Physiological effects)
whereas their trioxilin products...
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Hepoxilin B3
along with
their respective tri-hydroxyl metabolites,
trioxilin A3 and
trioxilin B3.
These metabolites have been
reported to have anti-inflammatory...
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levels in skin of
hepoxilins A3 and B3, as well as
their metabolites,
trioxilins A3 and B3, are
greatly reduced. Furthermore, rat Aloxe3 has been implicated...
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decomposes to a
mixture of
hepoxilins and trihydroxy-eicosatetraenoic
acids (
trioxilins) that
possess R or S
hydroxy and R,S or S,R
epoxide residues at various...
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hepoxilin A3 (8-hydroxy-11S,12Sepoxy-(5Z,8Z,14Z)-eicosatrienoic acid) to
trioxilin A3 (8,11,12-trihydroxy-(5Z,9E,14Z)-eicosatrienoic acid) and hepoxilin...
