-
Tisagenlecleucel, sold
under the
brand name Kymriah, is a CAR T
cells medication for the
treatment of B-cell
acute lymphoblastic leukemia (ALL)
which uses...
- approved, such as
alipogene tiparvovec (2012),
Strimvelis (2016),
tisagenlecleucel (2017),
voretigene neparvovec (2017),
patisiran (2018), onasemnogene...
- to the FDA's
first two
approvals of CAR T
cells in 2017,
those for
tisagenlecleucel (Kymriah),
marketed by
Novartis originally for B-cell
precursor acute...
- as a
recent advance in
treating refractory and
relapsed DLBCL, NOS (
tisagenlecleucel,
axicabtagene ciloleucel,
lisocabtagene maraleucel).
Chimeric antigen...
- medications, such as the CD20
antibody rituximab and the CD19 CAR T cell
tisagenlecleucel. The
experimental drug TGN1412—also
known as Theralizumab—caused extremely...
- can
initiate a
cytotoxic response.[medical
citation needed] In 2017,
tisagenlecleucel was
approved by the FDA as a CAR-T
therapy for
people with
acute B-cell...
-
lymphoma with two
failed systemic treatments),
axicabtagene ciloleucel,
tisagenlecleucel (for
large B-cell lymphoma), and
brexucabtagene autoleucel (for mantle...
- high risk)
Kisqali (ribociclib)
Breast Cancer 1,231 2022
Kymriah (
tisagenlecleucel)
Acute lymphoblastic leukemia Lamisil (terbinafine)
Fungal infections...
- of
cytokine release syndrome ****ociated with the CAR T cell
therapy tisagenlecleucel".
Journal of
Hematology & Oncology. 11 (1): 35. doi:10.1186/s13045-018-0571-y...
- for years. His work led to the
development and
commercialization of
tisagenlecleucel, the
first FDA-approved cell therapy. 1978 -
Alpha Omega Alpha Medical...
