Definition of Thrombomodulin. Meaning of Thrombomodulin. Synonyms of Thrombomodulin

- Thrombomodulin (TM), CD141 or BDCA-3 is an integral membrane protein expressed on the surface of endothelial cells and serves as a cofactor for thrombin...
- increase the stability of the fibrin clot. Thrombin interacts with thrombomodulin. As part of its activity in the coagulation cascade, thrombin also promotes...
- and protein C's activation is greatly promoted by the presence of thrombomodulin and endothelial protein C receptors (EPCRs). Because of EPCR's role...
- intact vessels prevent blood clotting with a heparin-like molecule and thrombomodulin, and prevent platelet aggregation with nitric oxide and prostacyclin...
- specificity. Overall, CK5/6, along with other markers like calretinin and thrombomodulin, demonstrates high sensitivity for epithelioid mesothelioma, making...
- with Protein C and thrombin binding to a cell surface protein thrombomodulin. Thrombomodulin binds these proteins in such a way that it activates Protein...
- Thrombin escaping from a site of vascular injury binds to its receptor thrombomodulin (TM) on the intact cell surface. As a result, thrombin loses its procoagulant...
- When this occurs, endothelial cells downregulate substances such as thrombomodulin, which is a key modulator of thrombin activity. The result is a sustained...
- anticoagulation factors such as tissue factor pathway inhibitor and thrombomodulin. The effects of the cytokines may be amplified by TLR-4 engagement on...
- protects against DNA damage, suggested to be comparable to amifostine Thrombomodulin Activated protein C Chelation therapy, a countermeasure for treating...