- In
organosulfur chemistry,
thioacetals are the
sulfur (thio-)
analogues of
acetals (R−CH(−OR)2).
There are two classes: the less-common monothioacetals...
-
refers to
compounds of type R1R2C(SR)(SR') (R,R' ≠ H, also
known as a
thioacetal).
Besides protecting against nucleophilic addition or oxidation, acetals...
- reduction.
Thioacetal Liu, Bin; Thayumanavan, S. (December 2020). "Mechanistic
Investigation on
Oxidative Degradation of ROS-Responsive
Thioacetal/Thioketal...
-
ylides in the
Wittig reaction to give the
alkenes With
thiols to give the
thioacetal With
hydrazine or 1-disubstituted
derivatives of
hydrazine to give hydrazones...
-
Example of
desulfurization of
thioacetals using Raney nickel...
- Wolfrom, M. L.; Karabinos, J. V. (June 1944). "Carbonyl
Reduction by
Thioacetal Hydrogenolysis".
Journal of the
American Chemical Society. 66 (6): 909–911...
-
nickel is used in
organic synthesis for desulfurization. For example,
thioacetals will be
reduced to
hydrocarbons in the last step of the
Mozingo reduction:...
-
aluminium chloride.
Thioacetals and
thioketals feature C−S−C−S−C bond sequence. They
represent a
subclass of sulfides. The
thioacetals are
useful in "umpolung"...
- atoms).
Examples include acetylenes (H−CC−R),
methyl sulfides (H−CH2SR),
thioacetals (H−CH(SR)2, e.g. dithiane),
methylphosphines (H−CH2PR2), furans, thiophenes...
- Ultraviolet–visible
spectroscopy Organometallic chemistry Acetals Hemiacetals Thioacetals Ketals Alcohols and
alkyl halides, diols,
thiols Alkanes and cycloalkanes...
