-
effecting alkylation.
Alkyl groups can also be
removed in a
process known as
dealkylation.
Alkylating agents are
often classified according to
their nucleophilic...
-
prepared by
dealkylation of
alkylated pyridines,
which are
obtained as
byproducts in the
syntheses of
other pyridines. The
oxidative dealkylation is carried...
- The Friedel–Crafts
reactions are a set of
reactions developed by
Charles Friedel and
James Crafts in 1877 to
attach substituents to an
aromatic ring. Friedel–Crafts...
- (COMT)-catalyzed
methylation and/or glucuronide/sulfate conjugation; and (2) N-
dealkylation, deamination, and
oxidation to the
corresponding benzoic acid derivatives...
-
intestines with oral administration. This
occurs via
hydroxylation and N-
dealkylation.
Domperidone is
almost exclusively metabolized by CYP3A4/5,
though minor...
- para-hydroxylation,
aliphatic alpha- and beta-hydroxylation, N-oxidation, N-
dealkylation, and deamination. The
known metabolic pathways include: Methamphetamine...
-
similar reaction condition).
Under these conditions,
toluene undergoes dealkylation to
benzene and methane: C 6 H 5 CH 3 + H 2 ⟶ C 6 H 6 + CH 4 {\displaystyle...
- gene
product catalyzes the
decyanation of
cyanocobalamin as well as the
dealkylation of
alkylcobalamins including methylcobalamin and adenosylcobalamin. This...
- electron-withdrawing
group (EWG). The
reaction proceeds by
nucleophilic dealkylation of the
ester by the
halide followed by decarboxylation,
followed by hydrolysis...
- used due to it
being a
primary metabolite, the
product of
hepatic N-
dealkylation, of MDMA (ecstasy). It is also a
common adulterant of
illicitly produced...
