- 8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-
tetrahydropterin and triphosphate-forming). This
enzyme catalyses the
following reversible...
- reductase, 6-pyruvoyl
tetrahydropterin (2'-oxo)reductase, 6-pyruvoyl-
tetrahydropterin 2'-reductase, and pyruvoyl-
tetrahydropterin reductase. This enzyme...
-
transformation of 7,8-dihydroneopterin
triphosphate into 6-pyruvoyl
tetrahydropterin synthase. The
kinetic values for this
enzyme are KM = 8.1 μM and Vmax...
- 8-dihydropterin triphosphate-lyase (6-pyruvoyl-5,6,7,8-
tetrahydropterin-forming).
Other names in
common use
include 2-amino-4-oxo-6-[(1S,2R)-1...
- 6-carboxy-5,6,7,8-
tetrahydropterin ammonia-lyase. This
enzyme catalyses the
following chemical reaction 6-carboxy-5,6,7,8-
tetrahydropterin ⇌ {\displaystyle...
-
Tetrahydrobiopterin (BH4, THB), also
known as
sapropterin (INN), is a
cofactor of the
three aromatic amino acid
hydroxylase enzymes, used in the degradation...
-
transformed by 6-pyruvoyltetrahydropterin
synthase into 6-pyruvoyl-
tetrahydropterin. It is also used in the Queuosine/Archeosine Pathway.[citation needed]...
- Blau N (1997). "Mutations in the GTP
cyclohydrolase I and 6-pyruvoyl-
tetrahydropterin synthase genes". Hum. Mutat. 10 (1): 11–20. doi:10...
- 1016/S0021-9258(18)93832-9. PMID 14216443.
Fitzpatrick PF (1999). "
Tetrahydropterin-dependent
amino acid hydroxylases".
Annual Review of Biochemistry....
- 3'-phosphoadenosine 5'-phosphosulfate
synthase 2 PCBD1: 6-pyruvoyl-
tetrahydropterin synthase/dimerization
cofactor of
hepatocyte nuclear factor 1 alpha...
