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Squalene is an
organic compound. It is a
triterpene with the
formula C30H50. It is a
colourless oil,
although impure samples appear yellow. It was originally...
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Squalene monooxygenase (also
called squalene epoxidase) is a
eukaryotic enzyme that uses
NADPH and
diatomic oxygen to
oxidize squalene to 2,3-oxidosqualene...
- the
hydrogenated derivative of
squalene,
although commercial samples are
derived from nature. In
contrast to
squalene, due to the
complete saturation...
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Squalene synthase (SQS) or farnesyl-diphosphate:farnesyl-diphosphate
farnesyl transferase is an
enzyme localized to the
membrane of the
endoplasmic reticulum...
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Lanosterol and
cycloartenol are
derived from the
cyclization of the
triterpene squalene.
Steroids are
named after the
steroid cholesterol which was
first described...
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reacts with
squalene in a
reaction catalyzed by
squalene monooxygenase during sterol biosynthesis. Furthermore,
squalene binds to
squalene-hopene cyclases...
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Squalene-hopene
cyclase (SHC) (EC 5.4.99.17) or hopan-22-ol hydro-lyase is an
enzyme in the
terpene cyclase/mutase family. It
catalyzes the interconversion...
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Squalene methyltransferase (EC 2.1.1.262, TMT-1, TMT-2) is an
enzyme with
systematic name S-adenosyl-L-methionine:
squalene C-methyltransferase. This enzyme...
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terpene units. Animals,
plants and
fungi all
produce triterpenes,
including squalene, the
precursor to all steroids.
Triterpenes exist in a
great variety of...
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inhibits ergosterol synthesis by
inhibiting squalene epoxidase, an
enzyme that
catalyzes the
conversion of
squalene to lanosterol. In fungi,
lanosterol is...
