-
Spironolactone, sold
under the
brand name
Aldactone among others, is a
diuretic medication primarily used to
treat fluid build-up due to
heart failure...
- The
pharmacodynamics of
spironolactone, an
antimineralocorticoid and
antiandrogen medication,
concern its
mechanisms of action,
including its biological...
-
combination with
other drugs, for the
management of
chronic heart failure.
Spironolactone, the
first member of the class, is also used in the
management of hyperaldosteronism...
-
antagonists can also be used for
treatment of
primary hyperaldosteronism.
Spironolactone, a
steroidal aldosterone antagonist, is also used in
management of female...
-
aldosterone receptor antagonist (SARA).
Eplerenone is more
selective than
spironolactone at the
mineralocorticoid receptor relative to
binding at androgen, progestogen...
- Generally, the
starting dose is oral
spironolactone 100 mg/day (max 400 mg/day). 40% of
people will
respond to
spironolactone. For nonresponders, a loop diuretic...
- that have
their effect at
similar locations:
Aldosterone antagonists:
spironolactone,
which is a
competitive antagonist of aldosterone.
Aldosterone normally...
-
inhibitors finasteride and
dutasteride and the
steroidal AR
antagonist spironolactone have been ****ociated with
significantly reduced risk of
prostate cancer...
-
brand name
Yasmin among others. The
medication is an
analog of the drug
spironolactone.
Drospirenone is
taken by mouth.
Common side
effects include acne, headache...
- and
spironolactone has
mixed and
inconsistent effects on
hormone levels. In any case,
testosterone levels are
usually unchanged by
spironolactone. Studies...
