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Rofecoxib is a COX-2-selective
nonsteroidal anti-inflammatory drug (NSAID). It was
marketed by
Merck & Co. to
treat osteoarthritis,
rheumatoid arthritis...
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reduces the risk of
peptic ulceration and is the main
feature of celecoxib,
rofecoxib, and
other members of this drug class.
After several COX-2–inhibiting...
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heart attack. As a result,
certain COX-2
selective inhibitors—such as
rofecoxib—are no
longer used due to the high risk of
undiagnosed vascular disease...
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complicated upper gastrointestinal events are
similar between two groups. Like
rofecoxib's VIGOR trial, the
MEDAL Program was also criticized, this time due to...
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became the building-block for
synthesis of COX-2 inhibitors.
Celecoxib and
rofecoxib, the
first COX-2
inhibitors to
reach market, were
based on DuP-697. It...
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advice to
physicians regarding celecoxib's safety. The COX-2
inhibitor rofecoxib (Vioxx) was
removed from the
market in 2004 due to its risk. Like all...
- (traditional
NSAIDs block both
versions in general).
These drugs (such as
rofecoxib, celecoxib, and etoricoxib) are
equally effective analgesics when compared...
- the
dosage and its
effects are
comparable to
human medications such as
rofecoxib and piroxicam. Grapiprant has also been tested in humans, and was researched to...
- double-blind,
clinical trial comparing the
efficacy of nimesulide,
celecoxib and
rofecoxib in
osteoarthritis of the knee". Drugs. 63 (Suppl 1): 37–46. doi:10...
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Tanaka W, et al. (October 2000). "Comparative
inhibitory activity of
rofecoxib, meloxicam, diclofenac, ibuprofen, and
naproxen on COX-2
versus COX-1...