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Retinoblastoma (Rb) is a rare form of
cancer that
rapidly develops from the
immature cells of a retina, the light-detecting
tissue of the eye. It is the...
- The
retinoblastoma protein (protein name
abbreviated Rb; gene name
abbreviated Rb, RB or RB1) is a
tumor suppressor protein that is
dysfunctional in several...
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Trilateral retinoblastoma is a
malignant midline primitive neuroectodermal tumor occurring in
patients with
inherited uni- or
bilateral retinoblastoma. In most...
- the
retinoblastoma tumor suppressor protein.
Alfred Knudson, a
pediatrician and
cancer geneticist,
proposed that in
order to
develop retinoblastoma, two...
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concrete structures Retinoblastoma, a
childhood cancer of the eyes
caused by a
mutation in the
retinoblastoma protein Retinoblastoma protein, a
tumor suppressor...
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Retinoblastoma-like 1 (p107), also
known as RBL1, is a
protein that in
humans is
encoded by the RBL1 gene. The
protein encoded by this gene is similar...
- cancer.
During this transition, G1
cyclin D-Cdk4/6
dimer phosphorylates retinoblastoma releasing transcription factor E2F,
which then
drives the transition...
-
often called blasts.
Examples are nephroblastoma, medulloblastoma, and
retinoblastoma. The
suffix -blastoma is used to
imply a
tumor of primitive, incompletely...
- Flexner–Wintersteiner
rosettes (spoke-and-wheel
shaped cell
formation seen
mainly in
retinoblastoma) have been
described as a form of palisading. A Flexner–Wintersteiner...
-
Retinoblastoma-like
protein 2 is a
protein that in
humans is
encoded by the RBL2 gene.
Retinoblastoma-like
protein 2 has been
shown to
interact with:...
