-
RAS p21
protein activator 1 or
RasGAP (
Ras GTPase activating protein), also
known as RASA1, is a 120-kDa
cytosolic human protein that
provides two prin****l...
- for
efficient function, and
hence the
GAP for
Ras,
RasGAP, may bind to and
stabilize the
catalytic machinery of
Ras,
supplying additional catalytic residues...
- SYNGAP1
synaptic Ras GTPase activating protein 1
homolog (rat)". Kim JH, Liao D, Lau LF,
Huganir RL (April 1998). "Syn
GAP: a
synaptic RasGAP that ****ociates...
- RASA1 gene is
responsible for
making p120-
RasGAP protein. This
protein regulates the
RAS/MAPK
signaling pathway.
RAS/MAPK
signaling pathway is used for transmitting...
-
dramatically by an
accessory protein of the GTPase-activating
protein (
GAP) class, for
example RasGAP.[citation needed] In turn, KRAS can bind to
proteins of the...
- 2007. Scheffzek, K. et al. "The
Ras-
RasGAP Complex:
Structural Basis for
GTPase Activation and Its Loss in
Oncogenic Ras Mutants". Science. 277 (1997):...
- the 'catalytic domain' or
rasGAP domain. Note:
There are
distinctly different GAPs for the rap and rho/rac
subfamilies of
ras-like
proteins (reviewed in...
- oligodendrocytes. The
catalytic RasGAP activity of
neurofibromin is
located in a
central portion of the protein, that is
called the
GAP-related
domain (GRD). The...
-
RasGAP-related
domain (GRD) has
sequence homology to the Sar1 GTPase. It was
hypothesized that IQGAP1
would act as a
GTPase activating protein (
GAP)...
-
usually results in
Ras activation. The
normal rate of
Ras catalytic GTPase (GTP hydrolysis)
activity can be
increased by
proteins of the
RasGAP family, which...
