Definition of Presystemic. Meaning of Presystemic. Synonyms of Presystemic

Here you will find one or more explanations in English for the word Presystemic. Also in the bottom left of the page several parts of wikipedia pages related to the word Presystemic and, of course, Presystemic synonyms and on the right images related to the word Presystemic.

Definition of Presystemic

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Meaning of Presystemic from wikipedia

- The first p**** effect (also known as first-p**** metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the...
- administration (as succinate salt) has low bioavailability, partly due to presystemic metabolism—some of it gets broken down in the stomach and bloodstream...
- RJ, De Witt KE, Rajewski G, Ireland J (October 1996). "Absorption and presystemic metabolism of selegiline hydrochloride at different regions in the gastrointestinal...
- ISBN 978-3-642-60107-1. Aungst BJ, Matz N (26 August 2007). "Prodrugs to Reduce Presystemic Metabolism". In Stella V, Borchardt R, Hageman M, Oliyai R, Maag H, Tilley...
- 1982;22(2):175-9. Pond SM, Tong T, Benowitz NL, Jacob P, Rigod J (August 1981). "Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects"...
- ISBN 978-3-642-60107-1. Aungst BJ, Matz N (2007). "Prodrugs to Reduce Presystemic Metabolism". Prodrugs. Biotechnology: Pharmaceutical Aspects. Vol. V...
- ISBN 978-3-642-60107-1. Aungst BJ, Matz N (26 August 2007). "Prodrugs to Reduce Presystemic Metabolism". In Stella V, Borchardt R, Hageman M, Oliyai R, Maag H, Tilley...
- doi:10.1002/chir.20397. PMID 17393472. Berry BW, Jamali F (1991). "Presystemic and systemic chiral inversion of R-(-)-fenoprofen in the rat". The Journal...