- of
paratopes can
differ greatly between different species. In jawed-vertebrates, V(D)J
recombination can
result in
billions of
different paratopes. The...
- are
created and
released by
plasma B cells. Each IgG
antibody has two
paratopes.
Antibodies are
major components of
humoral immunity. IgG is the main...
-
through complementary binding sites,
called epitopes in
antigens and
paratopes in antibody. In an antibody, the Fab (fragment, antigen-binding) region...
-
antigen can be
characterized by its
ability to bind to an antibody's
paratopes.
Different antibodies have the
potential to
discriminate among specific...
- T cells. The part of an
antibody that
binds to the
epitope is
called a
paratope.
Although epitopes are
usually non-self proteins,
sequences derived from...
- each of the
heavy and the
light chain. The
variable domain contains the
paratope (the antigen-binding site),
comprising a set of complementarity-determining...
-
strongly correlated CDR loop and
interface movements into account,
antibody paratopes should be
described as
interconverting states in
solution with varying...
- membrane-bound
antibody that, like all antibodies, has two
identical paratopes that are
unique and
randomly determined. The BCR for an
antigen is a significant...
- more
constant (CH2 and CH3)
domains Light chain (green) with one
variable (VL) and one
constant (CL)
domain Antigen binding site (
paratope)
Hinge regions...
- epitope-binding
ability of the
paratope slightly,
creating new
clones of B
cells in the process. Some of the
newly created paratopes bind more
strongly to the...
