-
Paracaspases (human: MALT1) are
members of the C14
family of
cysteine proteases.
Paracaspases are
proteins related to
caspases present in
animals and...
- gene. It's the
human paracaspase.
Genetic ablation of the
paracaspase gene in mice and
biochemical studies have
shown that
paracaspase is a
crucial protein...
- of
cysteine proteases and thus
related to caspases,
orthocaspases and
paracaspases. The
metacaspases are arginine/lysine-specific, in
contrast to caspases...
- in the C14
family of
cysteine proteases.
Similar to
metacaspases and
paracaspases, the
orthocaspases cleave their protein substrates after an arginine...
-
Seshagiri S,
Koonin EV,
Dixit VM (October 2000). "Identification of
paracaspases and metacaspases: two
ancient families of caspase-like proteins, one...
- (2004). "Developmental cell
death in
dictyostelium does not
require paracaspase".
Journal of
Biological Chemistry. 279 (12): 11489–94. doi:10.1074/jbc...
- S.; Koonin, E. V.; Dixit, V. M. (October 2000). "Identification of
paracaspases and metacaspases: two
ancient families of caspase-like proteins, one...
- eukaryotes.
Biology portal Apoptosis Apoptosome Bcl-2
Emricasan Metacaspase Paracaspase Pyroptosis The
Proteolysis Map
Programmed cell
death Cellular anastasis...
- et al. (2018). "Ancient
Origin of the CARD-Coiled Coil/Bcl10/MALT1-Like
Paracaspase Signaling Complex Indicates Unknown Critical Functions".
Frontiers in...
-
activated by
different protein kinase C isoforms, and
recruit BCL10 and the
paracaspase MALT1 upon activation,
forming a so-called CBM complex.
There are four...
