-
Nociceptin/orphanin FQ (N/OFQ), a 17-amino acid neuropeptide, is the
endogenous ligand for the
nociceptin receptor (NOP, ORL-1).
Nociceptin acts as a...
- The
nociceptin opioid peptide receptor (NOP), also
known as the
nociceptin/orphanin FQ (N/OFQ)
receptor or kappa-type 3
opioid receptor, is a
protein that...
-
endogenous opioids are dynorphins, enkephalins, endorphins,
endomorphins and
nociceptin. The
opioid receptors are ~40%
identical to
somatostatin receptors (SSTRs)...
- of
action involved. One
major pathway being through stimulation of the
nociceptin receptor, and
blocking this
receptor may
therefore be a
means of preventing...
- and κ-opioid receptors. It also has
relatively weak
affinity for the
nociceptin receptor.
Etorphine has an LD50 of 3 μg in humans. In Hong Kong, etorphine...
-
effectively does
nothing at all 3-Nitrooxypropanol, an
enzyme inhibitor Nociceptin receptor, a
neurotransmitter receptor in the
opioid receptor family Croatian...
-
Norbinaltorphimine is a
selective KOR
antagonist J-113,397 is a
selective nociceptin receptor (NOP)
antagonist Other selective antagonists are also known,...
- bind to
kappa receptors),
endorphins (mu receptors), endomorphins, and
nociceptin/orphanin FQ. The
opioid receptors are ~40%
identical to
somatostatin receptors...
- 1983. The PNOC gene
encoding prepronociceptin,
which is
cleaved into
nociceptin and
potentially two
additional neuropeptides. Adrenorphin, amidorphin...
- BTRX-140) –
selective k-opioid
receptor antagonist BTRX-246040 (LY-2940094) –
nociceptin receptor antagonist Scopolamine (DPI-386) –
muscarinic acetylcholine receptor...
