-
Neurofilaments (NF) are
classed as type IV
intermediate filaments found in the
cytoplasm of neurons. They are
protein polymers measuring 10 nm in diameter...
-
Neurofilament light polypeptide is a
protein that in
humans is
encoded by the NEFL gene.
Neurofilament light polypeptide is a
member of the intermediate...
-
copurifies with
other neurofilament subunits, as it was
originally discovered,
however in some
mature neurons it can be the only
neurofilament expressed. The...
- of biomarkers,
namely one
called neurofilament light chain (NFL), in
patients with Alzheimer's disease.
Neurofilament light chain is a
protein that is...
-
Neurofilament medium polypeptide (NF-M) is a
protein that in
humans is
encoded by the NEFM gene.
Neurofilaments are type IV
intermediate filament heteropolymers...
- from
peripherin protein dimers), but it can also
heteropolymerize with
neurofilaments in
several neuronal types. This
protein in
humans is
encoded by the...
- PMID 9846894 – via EuropeMC. M, Sjögren; E,
Englund (2004). "Negative
neurofilament light and tau
immunostaining in
frontotemporal dementia".
Dementia and...
-
towards a
slowing of progression, as well as a
significant reduction in
neurofilament light chain, a ****tive ALS
biomarker thought to
indicate neuronal damage...
- neurons, the
roles of
proteins showing loss of
nerve tissue such as
neurofilaments, tau, and N-acetylaspartate are
under investigation.
Improvement in...
-
recessive neurological disorder that
causes disorganization of
neurofilaments.
Neurofilaments form a
structural framework that
helps to
define the
shape and...
