-
Nalidixic acid (tradenames Nevigramon, NegGram,
Wintomylon and WIN 18,320) is the
first of the
synthetic quinolone antibiotics. In a
technical sense,...
- in humans.
Nalidixic acid was
discovered by
George Lesher and
coworkers in a
distillate during an
attempt at
chloroquine synthesis.
Nalidixic acid is thus...
- plants.
Bacterial DNA
gyrase is the
target of many antibiotics,
including nalidixic acid, novobiocin, albicidin, and ciprofloxacin. The
unique ability of...
- over
nalidixic acid.
Cinoxacin is
similar chemically (and in
antimicrobial activity) to
oxolinic acid and
nalidixic acid.
Relative to
nalidixic acid,...
- get into the bacterium. A real
example of cross-resistance
occurred for
nalidixic acid and ciprofloxacin,
which are both
quinolone antibiotics. When bacteria...
-
research on the
antibiotic nalidixic acid. In
addition to
behaving as an antibiotic, it was
found that many
derivatives of
nalidixic acid have
either stimulant...
- 55
Nalidixic acid 96.55
Cotrimoxazole 72.41
Ciprofloxacin 62.07
Ceftazidime 44.83
Ofloxacin 37.93
Ceftriaxone 34.48
Shigella dysenteriae 19
Nalidixic acid...
-
later found to be unnecessary, so omitted. Low
levels of
penicillin and
nalidixic acid are also
present in LJ
medium to
inhibit growth of Gram-positive...
-
inhibitory growth media such as deoxycholate, Salmonella-Shigella, and
nalidixic acid-cetrimide agars. It is
usually resistant to a
variety of antibiotics...
- class, of
which nalidixic acid is
often credited as the
first to be discovered. Like
other antibiotics before it the
discovery of
nalidixic acid has been...
